We read with interest the comments regarding our recently published article “Pituitary apoplexy in an adolescent male with macroprolactinoma presenting as middle cerebral artery territory infarction” and have addressed them below to the best of our knowledge [1].

Firstly, we accept the raised point based on recent published literature that patients presenting with pituitary apoplexy should be tested for coronavirus disease 2019 (COVID-19). However, the mentioned adolescent patient presented before the onset of COVID-19 pandemic and hence could not have been tested for it. Prepandemic, this case has been presented as a poster in annual meeting of European Society of Paediatric Endocrinology in September 2019 in Vienna, Austria [2].

Secondly, the article does not claim that our patient is the third adolescent patient with pituitary apoplexy. The uniqueness of this case is due to the presentation with ischemic stroke secondary to pituitary apoplexy, and we could find only two cases previously reported with similar presentation [3,4].

Thirdly, partial occlusion is a commonly used term. Regrettably, we do not agree that the word “occlusion” is used only in the context of “all or none” situation. Computed tomography angiography, with sensitivity and specificity of up to 98%, has been shown to be highly accurate for the detection of arterial occlusion and hence extremely unlikely to have missed an occlusion elsewhere [5]. We speculate that the presence of ischemic stroke only in the territory of left middle cerebral artery was due to presence of good collateral blood vessels in the right middle cerebral artery region.