Two Cases of Pheochromocytoma Presented with Hypertension and Weight Loss.

Kim,  Yoo Mi; Jin,  Hye Young; Khang,  Shin Kwang; Kim,  Kyu Rae; Lee,  Sang Ryung; Choi,  Jin Ho; Yoo,  Han Wook

Ann Pediatr Endocrinol Metab > Volume 15(2); 2010 > Article

Case Report

Journal of Korean Society of Pediatric Endocrinology 2010;15(2): 145-149.

Two Cases of Pheochromocytoma Presented with Hypertension and Weight Loss.

Yoo Mi Kim, Hye Young Jin, Shin Kwang Khang, Kyu Rae Kim, Sang Ryung Lee, Jin Ho Choi, Han Wook Yoo

¹Division of Pediatric Endocinology and Metabolism, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea. hwyoo@amc.seoul.kr
²Department of Pathology, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea.

Abstract

Pheochromocytoma is a rare disease in children, arising from chromaffin cells of adrenal medullary or extra-adrenal paraganglionic tissues. Typical clinical features include hypertension, diaphoresis, headache, and weight loss. It should therefore be considered that patients associated with hypertension might have pheochromocytoma. The diagnostic approach is based on typical clinical manifestations and biochemical test. Pheochromocytoma is completely curable by surgical resection. Early diagnosis and total excision are the most important aspects of accurate treatment of pheochromocytoma in children. We report two patients with pheochromocytoma presented with hypertension and weight loss both of which were improved after tumor resection.

Keywords: Hypertension;Pheochromocytoma