A Case of Sertoli Cell Tumor Presented with Sexual Precosity.

Cho,  Hyun Jung; Yang,  Seung; Oh,  Phil Soo; Shin,  Jeh Hoon

Ann Pediatr Endocrinol Metab > Volume 9(1); 2004 > Article

Case Report

Journal of Korean Society of Pediatric Endocrinology 2004;9(1): 86-90.

A Case of Sertoli Cell Tumor Presented with Sexual Precosity.

Hyun Jung Cho, Seung Yang, Phil Soo Oh, Jeh Hoon Shin

Abstract

Some sexual differentiation disorders are associated with gonadal neoplasia and increased incidence of testicular tumors has been discribed in the patients with, XY gonadal dysgenesis. The incidence of testicular tumors in infants and children are rare, representing only 1% of all pediatric solid tumors. In general, gonadal stromal tumors are one of the most characteristic endocrine tumors of the testis, endocrine activity occurs in at least 10-20%, among them Leydig cell tumors and Sertoli cell tumors are clinically important. Although the exact pathogenesis is unknown, endocrine activity due to estrogen secretion can be manifested clinically with gynecomastia or precocious puberty. We experienced and reported a child who visited for sexual precocity and had XY gonadal dysgenesis with Sertoli cell tumor.