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Ann Pediatr Endocrinol Metab > Volume 19(3); 2014 > Article |
Variable | Xp (n=10) | Xm (n=15) | Xm_Yseq (n=8) | P-value |
---|---|---|---|---|
CA at start GH (yr) | 7.2±3.0 | 9.0±3.4 | 9.2±2.6 | 0.344 |
BA at start GH (yr) | 5.8±2.8 | 8.3±3.4 | 8.3±2.9 | 0.149 |
BA delay (yr) | 1.39±1.12 | 0.73 ±1.58 | 0.84±0.60 | 0.427 |
Z_MPH | –0.36±0.90 | –0.72±1.01 | –0.13±0.51 | 0.245 |
Z_Ht_Lyon | 0.75±0.61a) | 1.08±0.74a) | 2.21±1.39a) | 0.047 |
Z_Ht_07Kor | –2.5±0.61 | –2.44±0.71 | –1.75±1.03 | 0.193 |
Z_BMI_07Kor | –0.17±1.57 | 0.78±0.88 | 0.81±0.96 | 0.070 |
Values are presented as mean±standard deviation.
The differences in the means of continuous variables (baseline Z_Ht_Lyon) with heterogenous variance between the 3 groups were tested by Welch’s analysis of variance (ANOVA).
TS, Turner syndrome; CA, chronological age; GH, growth hormone; BA, bone age; BA delay, difference between CA and BA; Z_MPH, midparental height z-score; Z_Ht_Lyon, height z-score according to Turner syndrome specific height reference by Lyon et al. [12]; Z_Ht_07Kor, height z-score according to the 2007 Korean reference height values; Z_BMI, body mass index z-score.
Values are presented as mean±standard deviation.
The differences in the means of nonnormally distributed variables (GH dose IU/kg/wk (0–3 yr), GH dose IU/kg/wk (0–1 yr), GH dose IU/kg/wk (1–2 yr), and GH dose IU/kg/wk (2–3 yr) were tested by Kruskal-Wallis testb). Other variables between the 3 groups were normally distributed. Analysis of variance was used for other variables with homogeneous variance. The difference in the means of variables within 2 subsets was analyzed using the Bonferroni method with P set at 0.025 (a)P<0.025).
GH, growth hormone; Z_Ht_Lyon, height z-score according to Turner syndrome specific height reference by Lyon et al. [12]; Z_Ht_07Kor, height z-score according to the 2007 Korean reference height values; Z_BMI, body mass index z-score; ΔZ_Ht_Lyon, change in Z_Ht_Lyon; and HV, height velocity.
S.E, Standard error; GH, growth hormone; Z_Ht_Lyon, height z-score according to Turner syndrome specific height reference by Lyon et al. [12]; BA, bone age; BA delay, difference between CA and BA; Xp, paternally derived X chromosome; Xm, maternally derived X chromosome; Xm_Yseq, 45,X/46,X,+mar(Y); Z_MPH, midparental height z-score; First- and second-year ΔZ_Ht_Lyon, first- and second-year change in Z_Ht_Lyon (first- and secondyear height response).
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