Pituitary Hyperplasia Secondary to Hypothyroidism Caused by Hashimoto's Thyroiditis in a Female Adolescent.

Kim,  Jeoung Suk; Kim,  Min Sun; Kim,  Sun Jun; Chung,  Gyung Ho; Hwang,  Pyoung Han; Lee,  Dae Yeol

doi:2011.16.3.185

Ann Pediatr Endocrinol Metab > Volume 16(3); 2011 > Article

Case Report

Journal of Korean Society of Pediatric Endocrinology 2011;16(3): 185-188.

DOI: https://doi.org/10.6065/jkspe.2011.16.3.185

Pituitary Hyperplasia Secondary to Hypothyroidism Caused by Hashimoto's Thyroiditis in a Female Adolescent.

Jeoung Suk Kim, Min Sun Kim, Sun Jun Kim, Gyung Ho Chung, Pyoung Han Hwang, Dae Yeol Lee

¹Department of Pediatrics, Chonbuk National University Medical School, Jeonju, Korea. leedy@jbnu.ac.kr
²Research Institute of Clinical Medicine, Chonbuk National University Medical School, Jeonju, Korea.
³Department of Radiology, Chonbuk National University Medical School, Jeonju, Korea.

Abstract

The authors report a case of a 16-year-old girl with pituitary hyperplasia and primary hypothyroidism caused by Hashimoto's thyroiditis. She presented with growth arrest, and hormonal studies showed decreased level of free thyroxine (T4), and increased levels of thyroid-stimulating hormone (TSH) and prolactin. A pituitary magnetic resonance imaging (MRI) showed a suprasellar mass. After 2 months of thyroxine replacement, thyroid function and high prolactin levels normalized, and the pituitary hyperplasia disappeared. This case represents relatively rapid normalization of pituitary hyperplasia, compare to the previous studies.

Keywords: Pituitary gland;Hyperplasia;Hypothyroidism