Follow-up Study of Hyperthyrotropinemia Detected by Neonatal Screening Test.

Paik,  Kyung Hoon; Kim,  Sung Hye; Jin,  Dong Kyu

Ann Pediatr Endocrinol Metab > Volume 7(2); 2002 > Article

Original Article

Journal of Korean Society of Pediatric Endocrinology 2002;7(2): 215-220.

Follow-up Study of Hyperthyrotropinemia Detected by Neonatal Screening Test.

Kyung Hoon Paik, Sung Hye Kim, Dong Kyu Jin

Abstract

PURPOSE
To understand natural course of transient hyperthyrotropinemia, so that the unnecessary treatment could be avoided. METHODS: Total 182 healthy newborns whose TSH levels in newborn screening test had been higher than 20 microIU/mL were recalled. Their serum levels of TSH, T4, free T4 were checked.
RESULTS
Among 182 newborns, 10 newborns had congenital hypothyroidism. 68.1 % of healthy newborns who had high TSH levels were normalized within 2 months and all of the rests were normalized within 5 months.
CONCLUSION
Transient hyperthyrotropinemia in newborns improves spontaneously. The unnecessary treatment of transient hyperthyrotropinemia should be avoided.

Keywords: TSH;Hyperthyrotropinemia;Congenital hypothyroidism