| A Case of Antithyroid Drug-Induced Agranulocytosis Treated with Granulocyte Colony-Stimulating Factor (G-CSF) and Methylprednisolone. |
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Tae Hoon Eom, Hye Jin Jeoun, Sang Min Cho, Min Ho Jung, Byung Kyu Suh, Byung Churl Lee |
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| Abstract |
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Although rare, agranulocytosis is the most serious, potentially fatal side effect of antithyroid drug. We experienced a 13-year-old girl who developed methimazole-induced agranulocytosis at 1 month after the initiation of treatment. Her granulocyte count recovered after discontinuation of methimazole and treatment with broad spectrum-antibiotics, G-CSF, and methylprednisolone.
After recovery from agranulocytosis she was treated with radioiodine ablation therapy. Early detection and proper management of antithyroid drug-induced agranulocytosis is very important. |
| Keywords:
Agranmulocytosis;Methimazole;G-CSF |
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