Aplasia Cutis Congenita in a Baby born to Hyperthyroid Mother Treated with Methimazole During Pregnancy: A Case Report.

Kim,  Myo Jing; Kim,  Mi Jin; Cho,  Gyu Rang; Chueh,  Hee Won; Jung,  Jin A; Lee,  Young Souk; Kim,  Young Hoon; Yoo,  Jae Ho

Ann Pediatr Endocrinol Metab > Volume 13(1); 2008 > Article

Case Report

Journal of Korean Society of Pediatric Endocrinology 2008;13(1): 100-103.

Aplasia Cutis Congenita in a Baby born to Hyperthyroid Mother Treated with Methimazole During Pregnancy: A Case Report.

Myo Jing Kim, Mi Jin Kim, Gyu Rang Cho, Hee Won Chueh, Jin A Jung, Young Souk Lee, Young Hoon Kim, Jae Ho Yoo

¹Department of Pediatrics, College of Medicine, Dong-A University, Busan, Korea. pedendo@dau.ac.kr
²Department of Dermatology, College of Medicine, Dong-A University, Busan, Korea.

Abstract

Aplasia cutis congenita is a rare congenital anomaly characterized by focal absence of skin at birth. It most commonly manifests as a solitary defect on the scalp, but sometimes it may occur as multiple lesions. Frieden classified aplasia cutis congenita into nine types according to the associated anomalies, but a unifying theory has not been identified to explain the etiology of this disease. We report a case of a newborn with isolated aplasia cutis congenita on the scalp at birth, whose mother was treated with methimazole up to the 22 weeks of gestation due to hyperthyroidism.

Keywords: Aplasia cutis congenita;Methimazole