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Ann Pediatr Endocrinol Metab > Volume 13(1); 2008 > Article
Aplasia Cutis Congenita in a Baby born to Hyperthyroid Mother Treated with Methimazole During Pregnancy: A Case Report.
Myo Jing Kim, Mi Jin Kim, Gyu Rang Cho, Hee Won Chueh, Jin A Jung, Young Souk Lee, Young Hoon Kim, Jae Ho Yoo
1Department of Pediatrics, College of Medicine, Dong-A University, Busan, Korea. pedendo@dau.ac.kr
2Department of Dermatology, College of Medicine, Dong-A University, Busan, Korea.
Abstract
Aplasia cutis congenita is a rare congenital anomaly characterized by focal absence of skin at birth. It most commonly manifests as a solitary defect on the scalp, but sometimes it may occur as multiple lesions. Frieden classified aplasia cutis congenita into nine types according to the associated anomalies, but a unifying theory has not been identified to explain the etiology of this disease. We report a case of a newborn with isolated aplasia cutis congenita on the scalp at birth, whose mother was treated with methimazole up to the 22 weeks of gestation due to hyperthyroidism.
Keywords: Aplasia cutis congenita;Methimazole
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